Commentary|Podcasts|September 15, 2025

ImmunoLogic, Episode 6: "The Future of Personalized Cancer Vaccines”

In Episode 6 of ImmunoLogic, Stephen Schoenberger, PhD, discussed his research on customized cancer vaccines.

Episode Breakdown

  • 0:00 – Intro and guest introduction
  • 4:24 – Challenges and progress in cancer vaccines
  • 8:24 – Identifying and prioritizing neoantigens
  • 14:01 – Advances in vaccine formulation and delivery
  • 22:52 – The future of personalized cancer vaccines
  • 28:37 – The role of CD4+ T-cells and antigen-presenting cells
  • 31:49 – Conclusion

We're excited to introduce another episode of the ImmunoLogic video podcast, hosted by Joseph Fraietta, PhD, an assistant professor of microbiology and the director of the Fraietta Lab at the University of Pennsylvania! Fraietta is joined by cohost Janna Minehart, MD, a clinical fellow in oncology (MSTR Program) at the University of Pennsylvania. Our hope is that this show will serve as a critical forum for clinicians, translational researchers, and biotech professionals to explore the evolving landscape of immunotherapy. We're seeking to bridge cutting-edge research with practical applications and delve into how immune-based therapies transition from innovative discoveries to transformative patient care solutions.

In this episode, the cohosts speak with Stephen Schoenberger, PhD, a professor at the Center for Cancer Immunotherapy at the La Jolla Institute, about his research into personalized cancer vaccines. Schoenberger, Fraietta, and Minehart covered topics including challenges and progress in cancer vaccines, identifying and prioritizing neoantigens, advances in vaccine formulation and delivery, the future of personalized cancer vaccines, and the role of CD4+ T-cells and antigen-presenting cells (APCs).

ImmunoLogic is tailored for an audience fluent in the language of medicine and biotechnology, offering data-driven insights while maintaining accessibility. This podcast is an essential resource for those driving the future of immunotherapy.

Interested in co-hosting an episode or being a guest? Have feedback to share? If you'd like to get in touch to talk about the show, contact our editorial director, Matt Hoffman: [email protected].

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