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Bryant Furlow

Articles

Are Older Women With RCC at Increased Risk With Adjuvant Sunitinib?

February 12, 2018

Adjuvant therapy with sunitinib after nephrectomy was associated with increased mortality among older women with renal cell carcinoma, according to a subgroup analysis of data from the ASSURE trial.

Lenalidomide Maintenance Therapy Outperforms Observation in Newly Diagnosed Multiple Myeloma

December 11, 2017

Continuous lenalidomide therapy improves outcomes among patients with newly diagnosed myeloma who are not autologous stem cell transplant candidates, according to findings from a large phase III clinical trial.

Epacadostat Plus Pembrolizumab Shows Early Promise in Advanced RCC

June 14, 2017

Epacadostat plus pembrolizumab yielded “encouraging response outcomes” among patients with 0 or 1 prior lines of therapy for advanced renal cell carcinoma.

CAR T Cell/Ibrutinib Combination May Improve CLL Response Rates

June 11, 2017

Despite immune-related adverse events, concurrent ibrutinib and anti-CD19 CAR T-cell therapy may improve response rates in patients with chronic lymphocytic leukemia.

Oncology Nurses Must Watch for CAR T-Cell Therapy Side Effects

May 09, 2017

It is increasingly important that nurses recognize cytokine release syndrome and other side effects that can be triggered by treatment with engineered CAR T-cell therapies.

An ‘Achilles' Heel’ for Kinase-Driven Leukemias?

April 13, 2017

Kinase oncoproteins and growth factors both activate the proto-oncogene c-FOS and DUSP1, allowing the persistence of residual leukemia cell populations despite tyrosine kinase inhibitor therapy.

Does Active Surveillance Benefit Patients With Metastatic RCC?

February 22, 2017

Active surveillance prior to initiating targeted therapy might benefit patients with metastatic renal cell carcinoma, since it delays therapy and toxicities.

Dacomitinib Shows Some Early Promise in Advanced Penile Cancers

February 21, 2017

Dacomitinib induction therapy has shown activity in HPV-negative, locally advanced or metastatic penile squamous cell carcinoma.