Michel Michaelides, MD, FACP, on Gene Therapy's Potential in Retinitis Pigmentosa
The professor of ophthalmology at the University College London Institute of Ophthalmology discussed the likely rise of gene therapies in inherited retinal diseases.
Janssen’s Gene Therapies Show Promise in Retinitis Pigmentosa, Geographic Atrophy
Both botaretigene sparoparvovec and JNJ-81201887 were well-tolerated in treated patients, according to data from the 2022 AAO meeting.
Gene Therapy Shows Promise in Leber Congenital Amaurosis
Significant improvements were reported in full-field stimulus testing.
Wet AMD Gene Therapy Reduces Anti-VEGF Treatment Burden
Participants in the AAVIATE trial had up to an 85% decrease in treatment burden 6 months after treatment with RGX-314.
Improving Outcomes in Corneal Endothelial Disease With Cell Therapy
Greg Kunst, chief executive officer, Aurion Biotech, discussed the potential of cell therapy in treating people with corneal endothelial disease around the world.
Optogenetics Device With Gene Therapy is Safe, Efficacious in Retinitis Pigmentosa
Following GS030 optogenetic therapy, the first treated patient was able to locate and count objects on a table and could identify crosswalks in the street.
Gene Therapy for Diabetic Macular Edema Shows Mixed Efficacy, Safety
Findings from the phase 2 INFINITY trial identified dose-dependent safety outcomes of ADVM-022 in patients with diabetic macular edema.
Gene Therapy Optogenetics Combination Efficacious in Retinitis Pigmentosa: José-Alain Sahel, MD
The professor from University of Pittsburgh School of Medicine discussed the combination of an optogenetics device and gene therapy in treatment of RP.
RGX-314 Gene Therapy Efficacious in Wet AMD: Robert L. Avery, MD
The chief executive officer of California Retina Consultants discussed the positive results of RGX-314 gene therapy in wet AMD.
OpRegen Shows Durable Efficacy in Dry AMD Geographic Atrophy
The Doheny Image Reading and Research Lab is leading a sub study to analyze OCT images with their proprietary 3D-OCTOR software.
Gene Therapy Represents New Era for Inherited Retinal Disease Treatment
Physician offers patient counseling pearls for selected retinal diseases.
New Data Shows Promise for Investigative XLRP Gene Therapy
The study presented at AAO provides an update on previously shared 6-month data from earlier this year.
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