ALS Awareness Month 2025: A Review of the Cell and Gene Therapy Pipeline

According to the ALS Association, a person is diagnosed with amyotrophic lateral sclerosis (ALS), progressive neurodegenerative disease affecting brain and spinal cord nerve cells, every 90 minutes. Diagnosis with ALS can take a substantial period of time—months or years—and although about 10% of patients can have their condition linked to an inherited mutated gene, 90% of cases are not known to be related to any genetic cause or family history. There is currently no cure for the condition.