CGTLive®’s Weekly Rewind – January 24, 2025

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Review top news and interview highlights from the week ending January 24, 2025.

CGTLive®’s Weekly Rewind

CGTLive®’s Weekly Rewind

Welcome to CGTLive®’s Weekly Rewind! We’ve compiled 5 highlights from this week’s coverage of advances in gene and cell therapies, including FDA actions, notable research, and interviews with experts across the field.

1. All of Atara Biotherapeutics’ T-Cell Immunotherapy Trials Placed on Clinical Hold by the FDA

The holds are related to a GMP compliance issue at a third-party manufacturing facility.

2. David Porter, MD, on Progress With Cross-Disciplinary Collaboration in Cell Therapy for Autoimmune Disease

The director of cell therapy and transplant at Penn Medicine also summed up his main message regarding the current state of the field in general.

3. First Patient Dosed in Phase 3 Trial for Intellia Therapeutics’ Hereditary Angioedema Gene Editing Therapy NTLA-2002

The company stated it expects to submit a BLA to the FDA next year.

4. Sarah Larson, MD, on Evaluating Lyell’s CAR-T IMPT-314 in LBCL

The medical director of the Immune Effector Cell Therapy Program at UCLA discussed initial data from a phase 1/2 trial.

5. Solid Biosciences’ INSPIRE DUCHENNE Study Puts DMD Gene Therapy SGT-003 to the Test

CGTLive took a closer look at the first-in-human clinical trial for the next-generation gene therapy.






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