CGTLive’s Weekly Rewind – July 15, 2022

Article

Review top news and interview highlights from the week ending July 15, 2022.

Welcome to CGTLive’s Weekly Rewind! We’ve compiled 5 highlights from this week’s coverage of advances in gene and cell therapies, including FDA actions, notable research, and interviews with experts across the field.

1. ATA188 Shows No Significant Improvements in MS, Study to Continue

There were not enough data at 6 months to predict expanded disability status scale (EDSS) improvements after treatment.

2. First Patient With Mesial Temporal Lobe Epilepsy Dosed With Neural Cell Therapy

Patient recruitment for the clinical trial is currently underway at epilepsy centers throughout the US.

3. First Patient With Familial Hypercholesteremia Dosed With Base-Editing Therapy

Verve Therapeutics is currently conducting a clinical trial in New Zealand and expects to be able to open trials in the UK and US later in 2022.

4. TCR T Cell Therapy for HBV-Related Liver Cancer Cleared for US Trial

SCG101 will be evaluated in trials across China, Singapore, and the US.

5. Legend Biotech Drops Lymphoma CAR T-Cell Therapy

Legend Biotech seeks to prioritize other product candidates in its pipeline.

Recent Videos
Chun-Yu Chen, PhD, a research scientist at Seattle Children’s Research Institute
William Chou, MD, on Targeting Progranulin With Gene Therapy for Frontotemporal Dementia
Alexandra Collin de l’Hortet, PhD, the head of therapeutics at Epic Bio
David Dimmock, MBBS, on Accelerating Therapy Discovery and Approval With AI David Dimmock, MBBS, on Accelerating Therapy Discovery and Approval With AI
Joshua M. Hare, MD, on Working to Address Unmet Needs in Alzheimer Disease With Lomecel-B Cell Therapy
David Dimmock, MBBS, on a Promising Case Study of Ultra-Rare, AI-Guided, ASO Development
William Chou, MD, on Expanding Frontotemporal Dementia Gene Therapy to Both GRN and C9orf72 Mutations
Scott Jeffers, PhD, on The Importance of Precise Reproducibility of AAVs
Michael Severino on In Vivo Gene Editing With RNA Gene Writers
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