CGTLive’s Weekly Rewind – June 2, 2023
Review top news and interview highlights from the week ending June 2, 2023.
Welcome to CGTLive™’s Weekly Rewind! We’ve compiled 5 highlights from this week’s coverage of advances in gene and cell therapies, including FDA actions, notable research, and interviews with experts across the field.
1. FDA Accepts Lifileucel's BLA for Advanced Melanoma With Priority Review
The BLA has a PDUFA action date of November 25, 2023.
2. Joseph Fraietta, PhD, on Investigating Molecular Pathways of CAR T-Cell Resistance
The assistant professor of microbiology at Penn Medicine discussed research into characterizing type 1 interferon and EGR2 signaling and their effects on CAR T-cell activation.
3. Genprex’s NSCLC Immunogene Therapy Trial Cleared to Begin Phase 2 Expansion Portion
Genprex also announced preliminary data from the phase 1 portion of the trial evaluating Reqorsa, which is being presented at ASCO’s 2023 meeting.
4. Rebecca Cottman, PhD, on Creating Regulated Gene Circuits to Enhance Cell Therapy Cytotoxicity
The scientist at Senti Biosciences discussed developing small molecule-regulated gene circuits.
5. PepGen’s Myotonic Dystrophy Oligonucleotide Trial Stalls
In more positive news, the company’s phase 2 trial for treating DMD will enroll patients in the second half of 2023.
Newsletter
Stay at the forefront of cutting-edge science with CGT—your direct line to expert insights, breakthrough data, and real-time coverage of the latest advancements in cell and gene therapy.
Related Articles
- Around the Helix: Cell and Gene Therapy Company Updates – September 17, 2025
September 17th 2025
- ImmunoLogic, Episode 6: "The Future of Personalized Cancer Vaccines”
September 15th 2025
- Top News in Lymphoma Cell Therapy for World Lymphoma Awareness Day 2025
September 15th 2025