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Jaime Rosenberg

Articles

Preclinical Models Suggest Promise of CAR-NK Cell Treatment in Several Solid Tumors

June 14, 2021

Previous research has suggested the efficacy of chimeric antigen receptor natural killer (CAR-NK) cells in hematological malignancies, and more recently, preclinical findings have raised the question of whether the type of treatment could be a viable, potentially more attractive option for solid tumors.

Researchers Outline Potential Strategies for Overcoming CAR-T Therapy Challenges

May 08, 2021

Strategies for improving outcomes across hematologic cancers and solid tumors range from addressing cytokine release syndrome and neurotoxicity mediators, immune rejection, on-target off-tumor toxicity, post-infusion control limitation, and immunosuppressive tumor microenvironment.

New Research Offers Key Safety, Early Efficacy Data on Zolgensma in SMA

September 25, 2020

A year after the FDA approved Zolgensma for the treatment of spinal muscular atrophy in children aged under 2 years without end-stage weakness, researchers shared safety and early efficacy data from the first 21 children treated with the gene therapy in Ohio.