Advantages of Concurrently Investigating Gene Therapies in Dogs and Humans

“From a perspective of gene expression, there's nothing to keep your expression profiles the same once you pass the age when you would typically procreate... there's no evolutionary pressure to keep things regulated. We're hoping that with the tools available today, we can piece something together to effectively reverse events that have occurred over your lifetime.”

REFERENCE

Davidsohn N, Pezone M, Vernet A, et al. A single combination gene therapy treats multiple age-related diseases. Proc. Natl. Acad. Sci. USA. Nov 2019, 116 (47) 23505-23511. doi: 10.1073/pnas.1910073116