CAR T Therapy in Non-Hodgkin Lymphoma: Kelly Garvin, BSN, RN

Video

The lymphoma specialist from Moffitt Cancer Center discussed the advantages of CAR T-cell therapy in non-Hodgkin lymphoma.

This content originally appeared on our sister site, OncLive.

OncLive spoke with Kelly Garvin, MA, BSN, RN, Moffitt Cancer Center, about the impact of CAR T-cell therapy on the treatment of patients with non-Hodgkin lymphoma.

Five FDA-approved CAR T-cell products are currently available for patients with certain hematologic malignancies, with even more indications expected in the future. For most patients with diffuse large B-cell lymphoma, treatment with immunotherapy and the chemotherapy regimen comprised of rituximab (Rituxan), cyclophosphamide, doxorubicin, vincristine, and prednisone can be curative; however, outcomes remain poor for those who do not respond to this approach, according to Garvin.

Currently, ongoing trials are examining CAR T-cell therapy vs standard of care in this patient population, to see whether the former modality can yield better outcomes, Garvin notes. If patients with poor prognostic factors can be identified early enough to utilize CAR T-cell therapy, outcomes could potentially be improved, Garvin concludes.

Newsletter

Stay at the forefront of cutting-edge science with CGT—your direct line to expert insights, breakthrough data, and real-time coverage of the latest advancements in cell and gene therapy.

Recent Videos
Nathan Yozwiak, PhD, the head of research at the GCTI
Derek Jackson, BS, MA, the vice president of cell & gene therapy product development at Pacira, and Kilian Guse, PhD, the vice president of genetic medicine platforms at Pacira
Derek Jackson, BS, MA, the vice president of cell & gene therapy product development at Pacira
Jeffrey Chamberlain, PhD
Tami John, MD
Tami John, MD
Tami John, MD
Matthew Ku, MBBS, FRACP, RACP, FRCPA/RCPA, PhD, an associate professor and the lymphoma stream lead at St Vincent’s Hospital
Saurabh Dahiya, MD, FACP, an associate professor of medicine at Stanford University School of Medicine; as well as clinical director of Cancer Cell Therapy in the Division of Blood and Marrow Transplantation and Cell Therapy at Stanford Medicine
Shahzad Raza, MD, a hematologist/oncologist at the Cleveland Clinic
Related Content
© 2025 MJH Life Sciences

All rights reserved.