Dr. Abid on Challenges With CAR T-Cell Therapy During the COVID-19 Pandemic

Video

Muhammad Bilal Abid, MD, MRCP, discusses challenges with CAR-T cell therapy during the coronavirus disease 2019 pandemic.

Muhammad Bilal Abid, MD, MRCP, assistant professor of medicine in the Divisions of Hematology/Oncology and Infectious Diseases at the Medical College of Wisconsin, discusses challenges with CAR-T cell therapy during the coronavirus disease 2019 (COVID-19) pandemic.

COVID-19 has caused many disruptions in the administration of CAR T-cell therapy​, says Abid. As such, several considerations need to be taken into account.

To mitigate the risk of severe cytokine release syndrome, ​CAR T-cell therapy should be brought to a temporary halt​, Abid explains. Doing so will prevent dysfunctional T cells and an elevation of inflammatory cytokines.

After stopping CAR T-cell therapy, it is critical to closely monitor patients, Abid concludes.

Related Videos
Faraz Ali, MBA, the chief executive officer of Tenaya Therapeutics
Faraz Ali, MBA, the chief executive officer of Tenaya Therapeutics
Evan Weber, PhD, an assistant professor of pediatrics at Children's Hospital of Philadelphia
Faraz Ali, MBA, the chief executive officer of Tenaya Therapeutics
Shankar Ramaswamy, MD, the cofounder, chairman, and CEO of Kriya Therapeutics
Kevin Campbell, PhD, a Howard Hughes Investigator at the University of Iowa
Debora Mazzetti, MS, on Multitargeting MicroRNA in Glioblastoma
Abhishek Gupta, BS, the senior vice president of genetic medicines at Syneos Health
Francesca Del Bufalo, MD, PhD, a medical doctor and scientist at Bambino Gesù Chidren’s Hospital
Luke Roberts, MBBS, PhD, on Early Clinical Data on Congestive Heart Failure Gene Therapy
© 2024 MJH Life Sciences

All rights reserved.