Treating Autoimmune Diseases With Smarter Cell Therapies
Karen Walker, chief technology officer, Kyverna Therapeutics, discussed the company’s CAR T-cell and regulatory T-cell technologies.
“We're looking at cell therapies for the treatment of autoimmune disease. Our lead indication is a CAR T so it's very similar to the ones that have been in the clinic for oncology, and we are looking at using them starting with the autologous platform... We are also looking at regulatory T cells which can suppress the immune response.”
The
One such company in attendance was Kyverna Therapeutics, which is developing cell therapies for autoimmune indications with candidates that will soon be advanced into the clinic. Its lead technology is a chimeric antigen receptor T cell (CAR T), while asynthetic regulatory T cell (synReg T cell) for B-cell autoimmune disorders is in the discovery phase. Both technologies are developed by use of Kyverna’s SmarTcell genetic engineering platform.
CGTLive spoke with Karen Walker, chief technology officer, Kyverna, to learn more about the company’s technologies and platforms. She also discussed challenges in the space and how Kyverna is aiming to meet them.
Newsletter
Stay at the forefront of cutting-edge science with CGT—your direct line to expert insights, breakthrough data, and real-time coverage of the latest advancements in cell and gene therapy.
Related Articles
- Around the Helix: Cell and Gene Therapy Company Updates – September 17, 2025
September 17th 2025
- ImmunoLogic, Episode 6: "The Future of Personalized Cancer Vaccines”
September 15th 2025
- Top News in Lymphoma Cell Therapy for World Lymphoma Awareness Day 2025
September 15th 2025