Ophthalmology

Many cell and gene therapy companies are initiating new programs and collaborations with the start of the new year.

Review some of our most-viewed coverage of advancements in cell therapies, including the latest study results and insights from experts in the field.

Vision loss was prevented in a mouse model of Fuchs endothelial corneal dystrophy.

Improved knowledge of the effects of mutations in the EYS gene may help inform new treatments.

Following GS030 optogenetic therapy, the first treated patient was able to locate and count objects on a table and could identify crosswalks in the street.

Current studies are using a polygenic risk score to evaluate the risk and clinical outcomes in primary open-angle glaucoma (POAG).

Findings from the phase 2 INFINITY trial identified dose-dependent safety outcomes of ADVM-022 in patients with diabetic macular edema.

Dan Oliver, cofounder and chief executive officer, Rejuvenate Bio, discussed the advantages of developing gene therapies for both dogs and humans.

The study is aiming to gain insight into glaucoma in African American populations.

The professor from University of Pittsburgh School of Medicine discussed the combination of an optogenetics device and gene therapy in treatment of RP.

Review top news and interview highlights from the week ending November 19, 2021.

The chief executive officer of California Retina Consultants discussed the positive results of RGX-314 gene therapy in wet AMD.

The Doheny Image Reading and Research Lab is leading a sub study to analyze OCT images with their proprietary 3D-OCTOR software.

Dan Oliver, cofounder and chief executive officer, Rejuvenate Bio, discussed the company’s ultimate goal of reversing aging.

The professor of medicine at Duke University School of Medicine previously served as commissioner in 2016.

Investigators are planning a first-in-man clinical trial for photoreceptor precursor transplant in Singapore.

Review top news and interview highlights from the week ending November 5, 2021.

4D Molecular Therapeutics announced positive data from trials assessing 2 of their gene therapies.

Partners in the Bespoke Gene Therapy Consortium include the NIH, FDA, private companies such as Pfizer and Biogen, and non-profits.

André Choulika, PhD, chief executive officer and cofounder, Cellectis, discussed the company’s expansion into gene therapies.

Researchers have developed a corneal epithelial stem cell-derived eye drop therapy for dry eye disease.

Review top news and interview highlights from the week ending October 29, 2021.

John Pollack, MD, discusses gene therapy advancements for retinal diseases.

Review top news and interview highlights from the week ending October 22, 2021.

The director of the Powell Gene Therapy Center at the University of Florida discussed improving access to gene therapies for patients with rare diseases worldwide.