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Rajni Agarwal-Hashmi, MD, on Safety Advantages of Gene Therapy in Fanconi Anemia Over SOC

The professor of pediatrics at Stanford Cancer Institute discussed recent data from clinical trials of the lentiviral gene therapy RP-L102.

Solid Tumor Cell Therapy Combination Trial Cleared to Continue

There were no deaths or safety signals identified by the DSMB for the 3 treated patients in cohort 1.

Allogeneic CAR T Cleared for B-cell Malignancy Trials

Sana Biotechnology also plans to submit another IND for the same indications for a CD22-targeted CAR T later in 2022.

MSC Therapy Shows Promise in Diabetic Kidney Disease

No adverse events related to the infusions of stromal cells were reported.

Advanced Colorectal Cancer CAR T Cleared for Trial

The phase 1 portion of the trial assessing CNA3103 will start enrollment in Australia in the first half of 2023; the phase 2 portion will expand to the US.

Treatment Strategies for Patients with R/R LBCL

Experts provide their perspective on the treatment landscape for patients with relapsed-refractory (R/R) large B-cell lymphoma (LBCL).